Brand Names: Mydocalm, Mydeton
Generic Name: Tolperisone
This medication description is not meant for treatment prescription without the intervention of a specialist
Common Uses
Usually, Tolperisone is indicated in the treatment of acute muscle spasms in back pain and spasticity in neurological diseases.
Tolperisone is currently marketed in Europe as a centrally-acting muscle relaxant which reportedly has special advantages over other drugs of its class in that it is reported not to cause drowsiness or lethargy according to some manufacturers.
Besides claiming that "Tolperisone has an excellent efficacy & safety profile" these manufacturers also state that Tolperisone has the unique property of mediating muscle relaxation without concomitant sedation nor does it cause impairment of coordination, weakness, mental confusion or withdrawal phenomena in contrast to other muscle relaxants.
Tolperisone is reportedly used in the typical treatment of the following conditions:

• Pathologically increased tone of the cross-striated muscle caused by neurological diseases(damage of the pyramidal tract, multiocular sclerosis, myelopathy, encephalomyelitis)
• Spastic paralysis and other encephalopathies manifested with muscular dystonia
• Muscular hypertonicity and muscular contraction caused by the following:
• Spondlosis
• Spondylarthrosis
• Cervical and lumbar syndromes
• Arthrosis of the large joints
• Obliterating, atherosclerosis of the extremity vessels
• Diabetical angiopathy
• Thromboagiitis obliterans
• Raynaud's syndrome

How to Take:
According to various sources, the typical oral adult dose for Tolperisone is 150mg to 450mg in a 24-hour period divided into two or three doses. It is highly advised that dosage information be confirmed by information provided from the manufacturer and prescriber.
More detailed dosage information is as follows:
Adults over 12 years old:

• Oral:50mg to 150mg every 8 hours
• IM: 100mg every 12 hours.
• IV: 100mg over 24 hours.

Pediatric Dosage (minimum weight of 20 Kg. minimum age 6 years old):

• Oral dosage: 1.000 mg/kg every 8 hours.

Neonatal Dosage (minimum weight of 3 Kg.)

• 2.500 mg/kg every 8 hours.

Warning and Precautions:
Manufacturers report that Tolperisone should not be used in the following conditions:

• Myasthenia
• Children under 1 years of age
• Pregnancy
• Breastfeeding

Important:
It is believed that Tolperisone has few interactions with other medicines. However, this doesn't rule out any interactions that may or may not have been reported to care-givers thus far.
Some manufacturers have stated that Tolperisone may enhance the effects of other neuromuscular blocking agents.

Storage:
Tolperisone should be stored at room temperature in a container it comes in. Protect from heat, sun light and moisture. Do not store in the bathroom. Keep away from pets and children.
Possible Side Effects:

• In hypersensitivity: muscle weakness, headache, arterial hypotension, nausea, vomiting, dyspepsia
• Skin allergic reactions: skin rash, hives, Quincke's edema, anaphylactic shock.

The side effects and reactions listed above may not include all effects reported by the drug's manufacturer.

More Information:
The information given above is a summary. Your doctor, pharmacies or health care provider can provide more information about Tolperisone. Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Do not store medication with end term of storage.